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| Product Information |
Product Name: | Z-PGLU-HIS-OH |
Synonyms: | CBZ-L-PYROGLUTAMYL-L-HISTIDINE;Z-PYR-HIS-OH;Z-PYROGLUTAMYL HISTIDINE;Z-PGLU-HIS-OH |
CAS: | 42533-68-6 |
MF: | C19H20N4O6 |
MW: | 400.39 |
Z-Pyr-His-OH – Protected Histidine Peptide Intermediate |
Z-Pyr-His-OH (also known as CBZ-Pyroglutamyl-Histidine) is a specialized Pyr-His peptide intermediate widely used in modern peptide synthesis. As a Z-Pyr-His building block, it represents a highly stable protected amino acid His derivative, designed for efficient chain elongation and incorporation in advanced peptide drug development. Recognized as part of high-value pharmaceutical intermediates, this compound supports research and commercial production across biotechnology and pharmaceutical industries.
Production & Quality |
Protected Peptide Chemistry: Produced under controlled synthesis, ensuring the integrity of the Pyr-His protected derivative for histidine peptide chain extension in both solution and solid-phase methods.
SPPS Compatibility: Specifically engineered for Z-Pyr-His-OH in solid-phase peptide synthesis (SPPS), minimizing side reactions and enhancing yield.
High Purity Standards: Delivered at pharmaceutical-grade quality, meeting the stringent requirements of global pharmaceutical intermediate manufacturers.
Scalability & Reliability: Our facilities in China are equipped to serve global clients, positioning us among leading china pharmaceutical intermediate suppliers with CDMO support.
Applications & Benefits |
Drug Development: Serves as a Z-pyroglutamyl histidine linker intermediate for drug conjugates, enabling precise drug-carrier attachment.
Peptide Design: Facilitates the use of Z-Pyr-His-OH in cyclic peptide or peptidomimetic design, expanding possibilities for bioactive molecule engineering.
Research & Manufacturing: Essential in R&D and scalable commercial production for therapeutic peptides.
Custom Manufacturing: Tailored solutions available for pharma companies seeking pharmaceutical intermediates with specific purity or structural requirements
Why Choose Us? |
Expertise in protected amino acid and peptide intermediate chemistry
GMP-compliant manufacturing and global logistics network
Comprehensive documentation (COA, MSDS, technical package)
CDMO services for custom peptide intermediate development
Z-Pyr-His-OH is a key pharmaceutical intermediate that bridges peptide synthesis efficiency and advanced drug design. With strong production capability and technical expertise, we support global pharmaceutical companies in scaling from lab research to commercial manufacturing.
Contact us today for bulk supply, technical documents, or CDMO partnership.
| Product Information |
Product Name: | Z-PGLU-HIS-OH |
Synonyms: | CBZ-L-PYROGLUTAMYL-L-HISTIDINE;Z-PYR-HIS-OH;Z-PYROGLUTAMYL HISTIDINE;Z-PGLU-HIS-OH |
CAS: | 42533-68-6 |
MF: | C19H20N4O6 |
MW: | 400.39 |
Z-Pyr-His-OH – Protected Histidine Peptide Intermediate |
Z-Pyr-His-OH (also known as CBZ-Pyroglutamyl-Histidine) is a specialized Pyr-His peptide intermediate widely used in modern peptide synthesis. As a Z-Pyr-His building block, it represents a highly stable protected amino acid His derivative, designed for efficient chain elongation and incorporation in advanced peptide drug development. Recognized as part of high-value pharmaceutical intermediates, this compound supports research and commercial production across biotechnology and pharmaceutical industries.
Production & Quality |
Protected Peptide Chemistry: Produced under controlled synthesis, ensuring the integrity of the Pyr-His protected derivative for histidine peptide chain extension in both solution and solid-phase methods.
SPPS Compatibility: Specifically engineered for Z-Pyr-His-OH in solid-phase peptide synthesis (SPPS), minimizing side reactions and enhancing yield.
High Purity Standards: Delivered at pharmaceutical-grade quality, meeting the stringent requirements of global pharmaceutical intermediate manufacturers.
Scalability & Reliability: Our facilities in China are equipped to serve global clients, positioning us among leading china pharmaceutical intermediate suppliers with CDMO support.
Applications & Benefits |
Drug Development: Serves as a Z-pyroglutamyl histidine linker intermediate for drug conjugates, enabling precise drug-carrier attachment.
Peptide Design: Facilitates the use of Z-Pyr-His-OH in cyclic peptide or peptidomimetic design, expanding possibilities for bioactive molecule engineering.
Research & Manufacturing: Essential in R&D and scalable commercial production for therapeutic peptides.
Custom Manufacturing: Tailored solutions available for pharma companies seeking pharmaceutical intermediates with specific purity or structural requirements
Why Choose Us? |
Expertise in protected amino acid and peptide intermediate chemistry
GMP-compliant manufacturing and global logistics network
Comprehensive documentation (COA, MSDS, technical package)
CDMO services for custom peptide intermediate development
Z-Pyr-His-OH is a key pharmaceutical intermediate that bridges peptide synthesis efficiency and advanced drug design. With strong production capability and technical expertise, we support global pharmaceutical companies in scaling from lab research to commercial manufacturing.
Contact us today for bulk supply, technical documents, or CDMO partnership.
