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| Product Information |
Product Name | Ectoine ； Ectoin ; 2-Methyl-1,4,5,6-tetrahydro-pyrimidine-4-carboxylic acid ； Tetrahydromethylpyrimidinecarboxylic acid |
CAS NO. | 96702-03-3 |
Appearance | White crystalline powder |
Molecular Weight | 142.2 g/mol |
Quality Standard | 98% up by HPLC |
| COA Of Ectoine |
| Item | Specification | Result | Test Method |
Physical Properties | — | — | — |
Appearance | White Solid | White Solid | Visual Inspection |
Specific Rotation | >160 (c=1, CH₃OH) | 160.4 | Polarimetry |
Melting Point (℃) | 278-283 | 280 | Melting Point Apparatus |
Chemical Analysis | — | — | — |
Content (HPLC) | >99% | 99.8% | HPLC |
pH Value | — | — | — |
pH (0.1% Solution) | 5-7 | 5.56 | pH Meter |
pH (2% Solution) | 5-7 | 5.42 | pH Meter |
pH (10% Solution) | 5-7 | 5.49 | pH Meter |
Conclusion | Confirm to the Standard | — | — |
| Ectoine: Cellular Protection Technology Revolutionizing Skincare |
Ectoine, a natural protective molecule synthesized by extremophilic microorganisms, has emerged as a key ingredient in high-end skincare and medical fields due to its multiple biological protection benefits. This article explores how technological advancements empower its application in sensitive skin repair, anti-aging, and environmental protection.
| Core Process: Biofermentation and High-Purity Extraction |
1. Microbial Fermentation Technology
Strain Selection:
Utilizing halophilic bacteria (such as Halomonas elongata), CRISPR gene editing enhances Ectoine yield to 30 g/L.
Continuous Cultivation System:
Dynamic regulation of osmotic pressure and pH achieves efficient fermentation in 96 hours, reducing costs by 40%.
Membrane Separation and Purification:
Combining ultrafiltration and ion-exchange chromatography yields Pure Ectoine (purity ≥99%), meeting stringent safety standards for Ectoine for sensitive skin.
2. Stability Process Innovation
Microencapsulation Technology:
Encapsulating Ectoine within a phospholipid bilayer protects against heat (up to 45°C) and UV degradation, extending the shelf life of Ectoine serum to 36 months.
Low-Temperature Freeze-Drying:
Applied in Ectoine nasal spray for rhinitis, maintaining molecular activity and enabling rapid solubility.
| Formula Innovation: Multifunctional Synergy and Targeted Delivery |
1. Skin Barrier Repair System
Ectoine for Skin Barrier Repair:
Combined with ceramides and cholesterol in a 1:1:1 ratio to mimic natural lipid structures, increasing stratum corneum hydration by 30% within 72 hours.
Anti-Pollution Complex Formula:
In Ectoine in anti-pollution skincare, combining fullerene with Ectoine creates an electrostatic barrier, adsorbing PM2.5 and neutralizing free radicals.
2. Ingredient Comparison and Synergistic Combinations
Ectoine vs. Hyaluronic Acid:
Ectoine exhibits superior moisture retention in low-humidity environments (2x higher water retention at RH 40%) without the stickiness of hyaluronic acid.
Ectoine and Niacinamide Combination:
A 4% niacinamide combination using liposomal co-delivery technology simultaneously reduces sebum production by 18% and calms redness.
| Clinical Efficacy and Medical Applications |
1. Skin Health Management
Ectoine for Eczema and Dermatitis:
Clinical studies show that a 2% Ectoine cream reduces itch scores by 47% and repairs the damaged barrier in atopic dermatitis (Ectoine for atopic dermatitis relief).
Anti-Photoaging:
How does Ectoine protect against UV damage? By stabilizing protein structures, it reduces UV-induced collagen degradation (inhibiting MMP-1 activity by 60%).
2. Expansion in Medical Fields
Ectoine Eye Drops for Dry Eye Syndrome:
Nanoemulsion technology enhances corneal epithelial penetration, improving tear film stability.
Allergy Prevention:
Research on how Ectoine helps in allergy prevention confirms that it blocks histamine receptor signaling, reducing the frequency of seasonal rhinitis.
| Product Information |
Product Name | Ectoine ； Ectoin ; 2-Methyl-1,4,5,6-tetrahydro-pyrimidine-4-carboxylic acid ； Tetrahydromethylpyrimidinecarboxylic acid |
CAS NO. | 96702-03-3 |
Appearance | White crystalline powder |
Molecular Weight | 142.2 g/mol |
Quality Standard | 98% up by HPLC |
| COA Of Ectoine |
| Item | Specification | Result | Test Method |
Physical Properties | — | — | — |
Appearance | White Solid | White Solid | Visual Inspection |
Specific Rotation | >160 (c=1, CH₃OH) | 160.4 | Polarimetry |
Melting Point (℃) | 278-283 | 280 | Melting Point Apparatus |
Chemical Analysis | — | — | — |
Content (HPLC) | >99% | 99.8% | HPLC |
pH Value | — | — | — |
pH (0.1% Solution) | 5-7 | 5.56 | pH Meter |
pH (2% Solution) | 5-7 | 5.42 | pH Meter |
pH (10% Solution) | 5-7 | 5.49 | pH Meter |
Conclusion | Confirm to the Standard | — | — |
| Ectoine: Cellular Protection Technology Revolutionizing Skincare |
Ectoine, a natural protective molecule synthesized by extremophilic microorganisms, has emerged as a key ingredient in high-end skincare and medical fields due to its multiple biological protection benefits. This article explores how technological advancements empower its application in sensitive skin repair, anti-aging, and environmental protection.
| Core Process: Biofermentation and High-Purity Extraction |
1. Microbial Fermentation Technology
Strain Selection:
Utilizing halophilic bacteria (such as Halomonas elongata), CRISPR gene editing enhances Ectoine yield to 30 g/L.
Continuous Cultivation System:
Dynamic regulation of osmotic pressure and pH achieves efficient fermentation in 96 hours, reducing costs by 40%.
Membrane Separation and Purification:
Combining ultrafiltration and ion-exchange chromatography yields Pure Ectoine (purity ≥99%), meeting stringent safety standards for Ectoine for sensitive skin.
2. Stability Process Innovation
Microencapsulation Technology:
Encapsulating Ectoine within a phospholipid bilayer protects against heat (up to 45°C) and UV degradation, extending the shelf life of Ectoine serum to 36 months.
Low-Temperature Freeze-Drying:
Applied in Ectoine nasal spray for rhinitis, maintaining molecular activity and enabling rapid solubility.
| Formula Innovation: Multifunctional Synergy and Targeted Delivery |
1. Skin Barrier Repair System
Ectoine for Skin Barrier Repair:
Combined with ceramides and cholesterol in a 1:1:1 ratio to mimic natural lipid structures, increasing stratum corneum hydration by 30% within 72 hours.
Anti-Pollution Complex Formula:
In Ectoine in anti-pollution skincare, combining fullerene with Ectoine creates an electrostatic barrier, adsorbing PM2.5 and neutralizing free radicals.
2. Ingredient Comparison and Synergistic Combinations
Ectoine vs. Hyaluronic Acid:
Ectoine exhibits superior moisture retention in low-humidity environments (2x higher water retention at RH 40%) without the stickiness of hyaluronic acid.
Ectoine and Niacinamide Combination:
A 4% niacinamide combination using liposomal co-delivery technology simultaneously reduces sebum production by 18% and calms redness.
| Clinical Efficacy and Medical Applications |
1. Skin Health Management
Ectoine for Eczema and Dermatitis:
Clinical studies show that a 2% Ectoine cream reduces itch scores by 47% and repairs the damaged barrier in atopic dermatitis (Ectoine for atopic dermatitis relief).
Anti-Photoaging:
How does Ectoine protect against UV damage? By stabilizing protein structures, it reduces UV-induced collagen degradation (inhibiting MMP-1 activity by 60%).
2. Expansion in Medical Fields
Ectoine Eye Drops for Dry Eye Syndrome:
Nanoemulsion technology enhances corneal epithelial penetration, improving tear film stability.
Allergy Prevention:
Research on how Ectoine helps in allergy prevention confirms that it blocks histamine receptor signaling, reducing the frequency of seasonal rhinitis.
