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| Product Information |
Product name | Z-ARG(PMC)-OH CHA; Z-Amino Acids and Derivatives; Z-Amino acid series; Protect amino acid |
Other names | N-Cbz-N'-(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-L-arginine cyclohexylammonium salt; guanidino);Z-Arg(Pmc)-OH;Z-ARG(PMC)-OH CHA;Cyclohexanamine(S);Z-L-Arg(Pmc)-OH·CHA;Cbz-L-Arg(Pmc)-OH.CHA;Z-ARGININE(PMC)-OH CHA; -5-(3-((2,2,5,7,8-pentamethylchroman-6-yl); Nα-Z-Nω-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-L-arginine cyclohexylammonium salt |
CAS No. | 112160-33-5 |
Molecular Formula | C34H51N5O7S |
Molecular Weight | 673.86 |
Quality Standard | 98% up by HPLC |
Appearance | White powder |
| COA of Z-ARG(PMC)-OH CHA |
ITEMS | SPECIFICATION |
Appearance (visual) | White to off - white powder |
TLC qualitative | Rf conforms to reference |
Purity (HPLC) | ≥ 98.5% |
Assay(HClO₄) | ≥ 98% |
Enantiomeric purity | ≤ 0.1% D - Enantiomer |
BSE/TSE/GMO - free | Yes |
| Z-Arg(PMC)-OH · CHA – High-Purity Protected Arginine Building Block for Advanced Peptide Synthesis |
Z-Arg(Pmc)-OH · CHA (also known as Cbz-Arg(Pmc)-OH·CHA, CAS 112160-33-5) is a premium protected arginine building block widely used in peptide synthesis arginine derivative applications, particularly for complex cyclic peptides such as cyclic RGD pentapeptides. We specialize in manufacturing Z-Arg(PMC)-OH · CHA supplier ≥98% purity grade, optimized for high-yield and reproducible synthesis.
| Precision Manufacturing Process for Consistent Quality |
Our Z-Arg(PMC)-OH·CHA production follows a multi-step synthesis starting from pharmaceutical-grade L-arginine. Protection of the guanidino group is achieved using Pmc (2,2,5,7,8-pentamethylchroman-6-sulfonyl) under controlled reaction temperatures, while the N-terminus is protected with Z (Cbz) to create peptide building block Z-Cbz-Arg(Pmc)-OH cyclohexylammonium salt.
Key stages include:
Raw Material Verification
Incoming raw materials are verified against COA and identity tested to ensure compliance with Z-Arg(PMC)-OH · CHA technical documents COA SDS.
Protection & Coupling Steps
Precise stoichiometry control during coupling reactions ensures high selectivity and minimal side-product formation—critical for applications like buy Z-Arg(Pmc)-OH CHA for peptide synthesis.
Cyclohexylammonium Salt Formation
Final product is isolated as the CHA salt form for improved stability and handling, with careful control of Z-Arg(PMC)-OH.CHA molecular weight 673.86 and molecular formula C₃₄H₅₁N₅O₇S.
Purification & Drying
Multiple recrystallization steps yield ≥98% purity, meeting the strictest peptide manufacturing standards.
Quality Control & Packaging
Each batch undergoes HPLC, NMR, and MS testing. Storage recommendations follow Z-Arg(PMC)-OH.CHA storage and safety H315 H319 H335 guidelines.
| Applications in Peptide R&D |
Z-Arg(PMC)-OH·CHA is a crucial intermediate in the synthesis of peptides requiring arginine residues with guanidino group protection. It is especially valuable in solid-phase peptide synthesis (SPPS) and uses of Z-Arg(PMC)-OH · CHA in cyclic RGD pentapeptide synthesis, where orthogonal protection strategies are required.
| Product Information |
Product name | Z-ARG(PMC)-OH CHA; Z-Amino Acids and Derivatives; Z-Amino acid series; Protect amino acid |
Other names | N-Cbz-N'-(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-L-arginine cyclohexylammonium salt; guanidino);Z-Arg(Pmc)-OH;Z-ARG(PMC)-OH CHA;Cyclohexanamine(S);Z-L-Arg(Pmc)-OH·CHA;Cbz-L-Arg(Pmc)-OH.CHA;Z-ARGININE(PMC)-OH CHA; -5-(3-((2,2,5,7,8-pentamethylchroman-6-yl); Nα-Z-Nω-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-L-arginine cyclohexylammonium salt |
CAS No. | 112160-33-5 |
Molecular Formula | C34H51N5O7S |
Molecular Weight | 673.86 |
Quality Standard | 98% up by HPLC |
Appearance | White powder |
| COA of Z-ARG(PMC)-OH CHA |
ITEMS | SPECIFICATION |
Appearance (visual) | White to off - white powder |
TLC qualitative | Rf conforms to reference |
Purity (HPLC) | ≥ 98.5% |
Assay(HClO₄) | ≥ 98% |
Enantiomeric purity | ≤ 0.1% D - Enantiomer |
BSE/TSE/GMO - free | Yes |
| Z-Arg(PMC)-OH · CHA – High-Purity Protected Arginine Building Block for Advanced Peptide Synthesis |
Z-Arg(Pmc)-OH · CHA (also known as Cbz-Arg(Pmc)-OH·CHA, CAS 112160-33-5) is a premium protected arginine building block widely used in peptide synthesis arginine derivative applications, particularly for complex cyclic peptides such as cyclic RGD pentapeptides. We specialize in manufacturing Z-Arg(PMC)-OH · CHA supplier ≥98% purity grade, optimized for high-yield and reproducible synthesis.
| Precision Manufacturing Process for Consistent Quality |
Our Z-Arg(PMC)-OH·CHA production follows a multi-step synthesis starting from pharmaceutical-grade L-arginine. Protection of the guanidino group is achieved using Pmc (2,2,5,7,8-pentamethylchroman-6-sulfonyl) under controlled reaction temperatures, while the N-terminus is protected with Z (Cbz) to create peptide building block Z-Cbz-Arg(Pmc)-OH cyclohexylammonium salt.
Key stages include:
Raw Material Verification
Incoming raw materials are verified against COA and identity tested to ensure compliance with Z-Arg(PMC)-OH · CHA technical documents COA SDS.
Protection & Coupling Steps
Precise stoichiometry control during coupling reactions ensures high selectivity and minimal side-product formation—critical for applications like buy Z-Arg(Pmc)-OH CHA for peptide synthesis.
Cyclohexylammonium Salt Formation
Final product is isolated as the CHA salt form for improved stability and handling, with careful control of Z-Arg(PMC)-OH.CHA molecular weight 673.86 and molecular formula C₃₄H₅₁N₅O₇S.
Purification & Drying
Multiple recrystallization steps yield ≥98% purity, meeting the strictest peptide manufacturing standards.
Quality Control & Packaging
Each batch undergoes HPLC, NMR, and MS testing. Storage recommendations follow Z-Arg(PMC)-OH.CHA storage and safety H315 H319 H335 guidelines.
| Applications in Peptide R&D |
Z-Arg(PMC)-OH·CHA is a crucial intermediate in the synthesis of peptides requiring arginine residues with guanidino group protection. It is especially valuable in solid-phase peptide synthesis (SPPS) and uses of Z-Arg(PMC)-OH · CHA in cyclic RGD pentapeptide synthesis, where orthogonal protection strategies are required.
