 |
| Product Information |
Product Name: | Thiamine Pyrophosphate |
Synonyms: | ANEURINEPYROPHOSPHORIC ACID;COCARBOXYLASE;COCARBOXYLASE CHLORIDE;Thiamine, pyrophosphoric acid ester;[2-[3-[(4-Amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-5-yl]ethoxy-hydroxy-phosphoryl]oxyphosphonic acid chloride;Thiamine diphosphate chloride;Vitamin B1;Aneurinepyrophosphoric acid, Cocarboxylase, Thiamine pyrophosphate chloride |
CAS: | 154-87-0 |
MF: | C12H19ClN4O7P2S |
MW: | 460.767382 |
EINECS: | 205-836-1 |
| Thiamine Pyrophosphate (TPP) – Essential Coenzyme for Pharmaceutical and Nutritional Applications |
Thiamine Pyrophosphate (TPP), also known as cocarboxylase or thiamine diphosphate (CAS 154-87-0), is the active form of vitamin B1 and a crucial TPP coenzyme in cellular metabolism. Recognized as a critical TPP cofactor vitamin B1, it supports enzymatic reactions in energy production, making it an indispensable compound for pharmaceuticals, nutraceuticals, and biotechnology applications. As a reliable food supplement CDMO partner, we specialize in the production and scale-up of TPP with strict quality control.
| Production & Manufacturing Technology |
Our Thiamine Pyrophosphate is produced through advanced fermentation, phosphorylation, and purification processes, ensuring high purity and bioactivity.
Controlled synthesis: phosphorylation of thiamine hydrochloride under optimized pH and temperature
Purification: ion-exchange chromatography and crystallization to achieve pharmaceutical-grade TPP
Analytical validation: HPLC, UV, and MS testing to ensure structural integrity and stability
Scalable supply: from R&D batches to bulk commercial volumes under GMP and ISO quality systems
We also offer CDMO contract manufacturing for food supplement applications, supporting customized formulations and derivatives for specific therapeutic uses.
| Applications & Functional Benefits |
Pharmaceutical Applications
TPP acts as a coenzyme of pyruvate dehydrogenase and transketolase, vital in glucose metabolism. Clinical studies show that TPP prevents diabetic retinopathy in animal models, supporting its potential in diabetes management.
Nutraceuticals & Supplements
Widely used as a food supplement, TPP supports neurological function, energy metabolism, and cardiovascular health.
Biotechnology & Materials Science
TPP in preparation of chitosan nanoparticles is gaining attention in drug delivery systems, where it functions as a safe ionic crosslinking agent.
Research & Development
An essential biochemical reagent for studying enzyme mechanisms and metabolic pathways.
| Why Partner With Us? |
Proven expertise in TPP production and scale-up
Reliable global supplier of Thiamine Pyrophosphate with consistent purity
Full technical documentation (COA, MSDS, stability studies)
Strong R&D capabilities in pharmaceutical intermediate and food supplement CDMO
Thiamine Pyrophosphate bridges pharmaceutical innovation and nutritional health. With advanced production technology, customizable supply, and expert support in CDMO contract manufacturing for food supplement, we deliver high-quality TPP to meet the evolving needs of the pharmaceutical, nutraceutical, and biotech industries.
| Product Information |
Product Name: | Thiamine Pyrophosphate |
Synonyms: | ANEURINEPYROPHOSPHORIC ACID;COCARBOXYLASE;COCARBOXYLASE CHLORIDE;Thiamine, pyrophosphoric acid ester;[2-[3-[(4-Amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-5-yl]ethoxy-hydroxy-phosphoryl]oxyphosphonic acid chloride;Thiamine diphosphate chloride;Vitamin B1;Aneurinepyrophosphoric acid, Cocarboxylase, Thiamine pyrophosphate chloride |
CAS: | 154-87-0 |
MF: | C12H19ClN4O7P2S |
MW: | 460.767382 |
EINECS: | 205-836-1 |
| Thiamine Pyrophosphate (TPP) – Essential Coenzyme for Pharmaceutical and Nutritional Applications |
Thiamine Pyrophosphate (TPP), also known as cocarboxylase or thiamine diphosphate (CAS 154-87-0), is the active form of vitamin B1 and a crucial TPP coenzyme in cellular metabolism. Recognized as a critical TPP cofactor vitamin B1, it supports enzymatic reactions in energy production, making it an indispensable compound for pharmaceuticals, nutraceuticals, and biotechnology applications. As a reliable food supplement CDMO partner, we specialize in the production and scale-up of TPP with strict quality control.
| Production & Manufacturing Technology |
Our Thiamine Pyrophosphate is produced through advanced fermentation, phosphorylation, and purification processes, ensuring high purity and bioactivity.
Controlled synthesis: phosphorylation of thiamine hydrochloride under optimized pH and temperature
Purification: ion-exchange chromatography and crystallization to achieve pharmaceutical-grade TPP
Analytical validation: HPLC, UV, and MS testing to ensure structural integrity and stability
Scalable supply: from R&D batches to bulk commercial volumes under GMP and ISO quality systems
We also offer CDMO contract manufacturing for food supplement applications, supporting customized formulations and derivatives for specific therapeutic uses.
| Applications & Functional Benefits |
Pharmaceutical Applications
TPP acts as a coenzyme of pyruvate dehydrogenase and transketolase, vital in glucose metabolism. Clinical studies show that TPP prevents diabetic retinopathy in animal models, supporting its potential in diabetes management.
Nutraceuticals & Supplements
Widely used as a food supplement, TPP supports neurological function, energy metabolism, and cardiovascular health.
Biotechnology & Materials Science
TPP in preparation of chitosan nanoparticles is gaining attention in drug delivery systems, where it functions as a safe ionic crosslinking agent.
Research & Development
An essential biochemical reagent for studying enzyme mechanisms and metabolic pathways.
| Why Partner With Us? |
Proven expertise in TPP production and scale-up
Reliable global supplier of Thiamine Pyrophosphate with consistent purity
Full technical documentation (COA, MSDS, stability studies)
Strong R&D capabilities in pharmaceutical intermediate and food supplement CDMO
Thiamine Pyrophosphate bridges pharmaceutical innovation and nutritional health. With advanced production technology, customizable supply, and expert support in CDMO contract manufacturing for food supplement, we deliver high-quality TPP to meet the evolving needs of the pharmaceutical, nutraceutical, and biotech industries.
