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| Product Information |
Product name | N,O-Dimethylhydroxylamine Hydrochloride |
Synonyms | N,O-DiMethylhydroxylaMineHyd;MethanaMine,N-Methoxy-,hydrochloride(1:1);N,O-DimethylhydroxylamineHydrochloride;N,O-dimehtylhydroxylamine.HCL;N,O-ChemicalbookDimethylhydroxylaminehydrochloride≥99%(GC);O-Dimethylhydroxylaminehydrochloride;CAS:6638-79-5;n,o-dimethylhydroxylaminehydrochloridecas6638-79-5 |
CAS No. | 6638-79-5 |
Molecular Formula | C2H8ClNO |
Molecular Weight | 97.54 |
Quality Standard | 99% up by HPLC |
Appearance | White to off-white powder |
N,O-Dimethylhydroxylamine Hydrochloride CAS 6638-79-5 – A Key Weinreb Amide Reagent for Pharmaceutical Synthesis |
N,O-Dimethylhydroxylamine Hydrochloride (CAS 6638-79-5), also known as N-Methoxy-N-methylamine Hydrochloride, is an important organic synthesis reagent used in the preparation of Weinreb amides. With its distinctive N-methoxy-N-methyl functionality, this compound provides a practical building block for carbonyl chemistry and the development of pharmaceutical intermediates.
For pharmaceutical and fine chemical manufacturers, N,O-Dimethylhydroxylamine Hydrochloride plays a valuable role in synthetic routes requiring controlled amide formation and subsequent carbonyl transformations.
Chemical Properties and Synthesis Process |
The preparation of N,O-Dimethylhydroxylamine Hydrochloride generally involves controlled salt formation, followed by crystallization and purification. Process conditions are adjusted to achieve the required chemical purity, stability, and batch consistency.
Key manufacturing considerations include:
Precursor Preparation: The appropriate N,O-dimethylhydroxylamine intermediate is prepared and controlled according to the selected synthetic route.
Hydrochloride Salt Formation: Controlled hydrochloric acid addition converts the free-base intermediate into its hydrochloride salt.
Crystallization and Isolation: Solvent selection, temperature control, and crystallization conditions influence crystal formation and product recovery.
Purification and Drying: Filtration, washing, and controlled drying help reduce residual impurities and moisture.
Quality Evaluation: Assay, identification, melting range, water content, and impurity profiles are important parameters for evaluating product consistency.
These process factors are particularly relevant when producing material for pharmaceutical synthesis and downstream chemical transformations.
Applications in Pharmaceutical Intermediate Synthesis |
One of the most important applications of N,O-Dimethylhydroxylamine Hydrochloride CAS 6638-79-5 is the synthesis of Weinreb amides through reactions with suitable activated carboxylic acid derivatives.
Weinreb amides are valuable intermediates in organic synthesis because they enable controlled conversion into ketones through reactions with organometallic reagents. Their characteristic reaction behavior helps minimize excessive addition during carbonyl formation.
As a Weinreb Amide Reagent, this compound is therefore relevant to pharmaceutical intermediate development, API synthesis research, and specialty chemical manufacturing. It supports synthetic route development where selective carbonyl construction is required.
N,O-Dimethylhydroxylamine Hydrochloride Supply from Rocky Pharm |
For companies seeking a reliable N,O-Dimethylhydroxylamine Hydrochloride Supplier China, Rocky Pharm provides pharmaceutical raw material sourcing services through established supply channels in China.
Whether your requirement involves laboratory-scale evaluation, pilot production, or commercial quantities, we can assist with sourcing suitable material based on your purity specifications, procurement volume, and application requirements.
As an experienced N,O-Dimethylhydroxylamine Hydrochloride Bulk Supplier sourcing partner, Rocky Pharm welcomes inquiries from pharmaceutical intermediate producers, API developers, and international chemical distributors.
Contact Rocky Pharm for product information, current supply options, and a competitive quotation for CAS 6638-79-5.
