Edoxaban Intermediate 365998-36-3
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Edoxaban Intermediate 365998-36-3

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Product Information

Product name

Edoxaban Intermediate (avoid the patent)

Synonyms

(5H-Pyrrolo[3,4-d]thiazole-5-carboxylicacid,2-[[[(1R,2S,5S)-2-[[(5-chloro-1H-indol-2-yl)carbonyl]aMino]-5-[(diMethylaMino)carbonyl]cyclohexyl]aMino]carbonyl]-4,6-dihydro-,1,1-diMethylethylester;CarbaMicacid,N-[(1R,2S,5S)-2-aMino-5-[(diMethylaMino)carbonyl]cyclohexyl]-,1,1-diMChemicalbookethylethylester;EdoxabanINTERMEDIATESⅠ;EdoxabanINTERMEDIATESⅡ;EdoxabanINTERMEDIATESⅢ;InterMediateofEdoxaban;tert-Butyl[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate;Tert-Butyl[(1R,2S,5S)-2-aMino-5-[(diMethylaMino)carbonyl]cyclohexyl]carbaMate(forEdoxaban);tert-butyl (1R,2S,5S)-2-aMino-5-(diMethylcarbaMoyl)cyclohexylcarbaMate

CAS No.

365998-36-3

Molecular Formula

C14H27N3O3

Molecular Weight

285.38

Quality Standard

99% up by HPLC,S.Impurity < 0.1%

Appearance

White to off-white powder



Edoxaban Intermediate CAS 365998-36-3 – Pharmaceutical Intermediate for Anticoagulant API Production

In the development and manufacturing of anticoagulant drugs, the selection of suitable pharmaceutical intermediates plays an important role in maintaining production efficiency and product consistency. Edoxaban Intermediate CAS 365998-36-3 is a chemical building block associated with the synthesis of edoxaban, an oral anticoagulant that belongs to the direct factor Xa inhibitor class.


As an important Edoxaban API Intermediate, this compound is relevant to pharmaceutical companies engaged in the development and commercial production of anticoagulant APIs. Consistent chemical quality, controlled impurity levels, and reliable downstream compatibility are key considerations when sourcing this Edoxaban Intermediate for pharmaceutical manufacturing.


Manufacturing Process of Edoxaban Intermediate

The production of Edoxaban Intermediate CAS 365998-36-3 involves a controlled organic synthesis process. Manufacturing conditions are selected according to the compound's molecular structure and the established synthetic route. Several important stages contribute to the overall production process:

  • Starting Material Preparation: Suitable chemical raw materials are selected and prepared to meet the requirements of the synthesis route.

  • Chemical Reaction Control: Reaction parameters such as temperature, reaction time, reagent proportions, and solvent selection are carefully managed to support efficient conversion and minimize unwanted side reactions.

  • Intermediate Separation: Following the reaction, appropriate extraction, filtration, and separation operations are used to isolate the target compound.

  • Purification and Refinement: Suitable purification methods help reduce residual starting materials, reaction by-products, and other process-related impurities.

  • Quality and Process Evaluation: Analytical testing focuses on identity, assay, related substances, and other relevant quality attributes to assess consistency between production batches.


Effective process control helps ensure that the intermediate is suitable for subsequent chemical transformations during edoxaban API manufacturing.


Pharmaceutical Applications of Edoxaban Intermediate

The main application of Edoxaban API Intermediate is in the synthesis of edoxaban active pharmaceutical ingredient. Edoxaban works by inhibiting factor Xa, an important component of the blood coagulation pathway. Its pharmaceutical applications include the prevention and treatment of certain thromboembolic conditions.


For API manufacturers, a stable supply of this intermediate can support production scheduling, process optimization, and commercial manufacturing. It is particularly relevant to companies specializing in anticoagulant APIs and cardiovascular pharmaceutical products.



Edoxaban Intermediate Sourcing Support by Rocky Pharm

If your company is looking for Edoxaban Intermediate CAS 365998-36-3, Rocky Pharm can help you identify suitable sourcing options in the Chinese pharmaceutical raw material market. We cooperate with established suppliers and provide procurement support for international customers seeking reliable pharmaceutical intermediates.


Whether you are comparing an Edoxaban Intermediate Manufacturer, searching for an Edoxaban Intermediate Supplier China, or evaluating a CAS 365998-36-3 Supplier for long-term procurement, we can help connect your requirements with suitable supply resources. For pharmaceutical companies working with a qualified Pharmaceutical Intermediate Manufacturer, Rocky Pharm also offers sourcing assistance to support product procurement and supply planning.


Contact Rocky Pharm for product information, current market availability, and a quotation for your purchasing requirements.


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