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| Product Information |
Product name | Clozapine Intermediate |
Synonyms | 6-chloro-2,9-diazatricyclo[9.4.0.0,3,8]pentadeca-1(15),3,5,7,11,13-hexaen-10-one;Clozapineimpurity1/ClozapineEPImpurityA/ClozapineimpurityC(USP)/8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one;8-CHLORO-11-OXO-10,11-DIHYDRO-5H-DIBENZO-1,4-DIAZEPINE;8-CHLORO-5,Chemicalbook10-DIHYDRO-11H-DIBENZO[B,E][1,4]-DIAZEPIN-11-ONE;8-CHLORO-5,10-DIHYDRODEBENZO[B,E][1,4]DIAZEPIN-11-ONE;8-chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one;8-CHLORO-10,11-DIHYDRO-5H-DIBENZO[B,E][1,4]DIAZEPIN-11-ONE;8-Chloro-11-oxo-10,11-dihydro-5h-debenzo-1,4-diazepine;8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one |
CAS No. | 50892-62-1 |
Molecular Formula | C13H9ClN2O |
Molecular Weight | 244.68 |
Quality Standard | 99% up by HPLC,S.Impurity < 0.1% |
Appearance | White to off-white powder |
Clozapine Intermediate 50892-62-1 – Pharmaceutical Raw Material for Clozapine API Manufacturing |
Clozapine Intermediate 50892-62-1, chemically known as 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one, is an important heterocyclic compound used in the pharmaceutical industry as a key building block for clozapine production. Also referred to as an 8-Chloro Clozapine Intermediate, this compound plays a significant role in the preparation of the active pharmaceutical ingredient (API) and supports the manufacture of medicines used in the treatment of certain psychiatric disorders.
As a specialized Clozapine Raw Material, it is valued for its defined molecular structure and suitability for downstream pharmaceutical synthesis. Consistent material quality and controlled production are important factors for manufacturers seeking a reliable Clozapine API Intermediate.
Manufacturing Process of Clozapine Intermediate |
The production of Clozapine Intermediate 50892-62-1 involves a controlled organic synthesis process designed to obtain the target dibenzodiazepinone structure. Manufacturing typically focuses on the following stages:
Raw Material Selection: Appropriate starting materials are selected according to their identity, quality, and suitability for the intended synthesis route.
Chemical Synthesis: The target heterocyclic structure is prepared through controlled chemical reactions. Reaction conditions and processing parameters are managed to support product consistency and minimize unwanted by-products.
Purification and Refinement: The crude product undergoes suitable separation and purification operations to improve chemical quality and remove residual impurities.
Quality Control: Analytical testing is used to evaluate key quality attributes, such as identity, assay, related substances, and residual solvents, according to the applicable product specifications.
Batch Consistency: Production controls and process monitoring help maintain reproducibility across manufacturing batches and support downstream API production.
Applications in Pharmaceutical Manufacturing |
The primary application of 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one is as an intermediate in the synthesis of clozapine. Its chemical structure provides an essential foundation for subsequent transformation steps in the production of the finished API.
For pharmaceutical manufacturers, a dependable Clozapine Intermediate Bulk supply can support production planning, process continuity, and raw-material procurement. It is suitable for consideration by companies involved in pharmaceutical intermediate sourcing, API development, and commercial manufacturing.
Clozapine Intermediate Manufacturer and Supply |
When selecting a Clozapine Intermediate Manufacturer China, buyers should evaluate synthesis expertise, process control, product consistency, and production capacity. A professional Clozapine Intermediate Factory should focus on stable manufacturing operations and reliable batch-to-batch quality.
We aim to support pharmaceutical customers with a consistent supply of Clozapine Intermediate 50892-62-1, meeting their sourcing requirements for research, development, and industrial API manufacturing.
