 |
| Product Information |
| Product Name: | Boc-His(Trt)-Aib-Glu(Otbu)-Gly-OH |
| Synonyms: | Boc-His(Trt)-Aib-Glu(OBtu)-Gly-OH;Boc-L-His(Trt)-Aib-Glu(OtBu)-Gly-OH;Boc-His(Trt)-Aib-Glu(tBu)-Gly-OH;Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH;Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH Boc-His(Trt)-Aib-Glu(OBtu)-Gly-OH;Boc-His(Trt)-Aib-Glu(OtBU) Gly-ОH;((S)-5-(tert-Butoxy)-2-(2-((S)-2-((tert-butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-5-oxopentanoyl)glycine |
| CAS: | 1890228-73-5 |
| MF: | C45H56N6O9 |
| MW: | 824.98 |
| Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH – High-Purity Semaglutide Side Chain Intermediate |
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH (CAS 1890228-73-5) is a protected peptide building block and a key Semaglutide side chain intermediate. As a highly specialized amino acid derivative, it plays a vital role in the synthesis of GLP-1 receptor agonists, peptide drugs, and related medical intermediates. With extensive expertise in peptide CDMO and amino acid derivatives CDMO services, we provide consistent high-purity material for global pharmaceutical R&D and commercial manufacturing.
| Production & Manufacturing Technology |
Our manufacturing of Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH follows strict GMP-like process standards:
Raw Material Selection: Pharmaceutical-grade amino acid precursors with stringent quality control.
Protection Strategy: Use of Boc, Trt, Aib, and OtBu protective groups ensures stability and prevents side reactions during synthesis.
Purification: Multi-step crystallization and preparative chromatography deliver ≥98% purity for SPPS (solid-phase peptide synthesis).
Scalability: From gram-level research to multi-kilogram commercial batches with full traceability.
CDMO Services: End-to-end cdmo contract manufacturing for peptide and amino acid derivatives, including custom synthesis and analytical support.
| Applications & Use Cases |
Semaglutide Intermediate
As a critical Semaglutide intermediate Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH, it enables the synthesis of GLP-1 receptor agonist drugs for type 2 diabetes and obesity management.
Protected Peptide Building Block
Essential for solid-phase peptide synthesis (SPPS), it provides stability and efficiency in complex peptide assembly.
ADC & Linker Research
Applied as a medical intermediate in ADC linker development, expanding its role beyond GLP-1 analogues.
Custom Peptide & API Development
Trusted by pharmaceutical companies and research institutes, with Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH suppliers in China offering global distribution
| Why Choose Us as Your Manufacturing Partner? |
Proven expertise in cdmo contract manufacturing for peptide synthesis and amino acid derivatives
Reliable quality: ≥98% purity, full COA, HPLC, and NMR verification
Scalable production with competitive lead times
Technical documentation and regulatory support for IND/NDA projects
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH is more than a protected peptide building block—it is a cornerstone intermediate for next-generation peptide drugs such as Semaglutide. With our CDMO capabilities, we deliver high-quality solutions tailored to pharmaceutical innovation.
| Product Information |
| Product Name: | Boc-His(Trt)-Aib-Glu(Otbu)-Gly-OH |
| Synonyms: | Boc-His(Trt)-Aib-Glu(OBtu)-Gly-OH;Boc-L-His(Trt)-Aib-Glu(OtBu)-Gly-OH;Boc-His(Trt)-Aib-Glu(tBu)-Gly-OH;Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH;Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH Boc-His(Trt)-Aib-Glu(OBtu)-Gly-OH;Boc-His(Trt)-Aib-Glu(OtBU) Gly-ОH;((S)-5-(tert-Butoxy)-2-(2-((S)-2-((tert-butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-5-oxopentanoyl)glycine |
| CAS: | 1890228-73-5 |
| MF: | C45H56N6O9 |
| MW: | 824.98 |
| Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH – High-Purity Semaglutide Side Chain Intermediate |
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH (CAS 1890228-73-5) is a protected peptide building block and a key Semaglutide side chain intermediate. As a highly specialized amino acid derivative, it plays a vital role in the synthesis of GLP-1 receptor agonists, peptide drugs, and related medical intermediates. With extensive expertise in peptide CDMO and amino acid derivatives CDMO services, we provide consistent high-purity material for global pharmaceutical R&D and commercial manufacturing.
| Production & Manufacturing Technology |
Our manufacturing of Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH follows strict GMP-like process standards:
Raw Material Selection: Pharmaceutical-grade amino acid precursors with stringent quality control.
Protection Strategy: Use of Boc, Trt, Aib, and OtBu protective groups ensures stability and prevents side reactions during synthesis.
Purification: Multi-step crystallization and preparative chromatography deliver ≥98% purity for SPPS (solid-phase peptide synthesis).
Scalability: From gram-level research to multi-kilogram commercial batches with full traceability.
CDMO Services: End-to-end cdmo contract manufacturing for peptide and amino acid derivatives, including custom synthesis and analytical support.
| Applications & Use Cases |
Semaglutide Intermediate
As a critical Semaglutide intermediate Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH, it enables the synthesis of GLP-1 receptor agonist drugs for type 2 diabetes and obesity management.
Protected Peptide Building Block
Essential for solid-phase peptide synthesis (SPPS), it provides stability and efficiency in complex peptide assembly.
ADC & Linker Research
Applied as a medical intermediate in ADC linker development, expanding its role beyond GLP-1 analogues.
Custom Peptide & API Development
Trusted by pharmaceutical companies and research institutes, with Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH suppliers in China offering global distribution
| Why Choose Us as Your Manufacturing Partner? |
Proven expertise in cdmo contract manufacturing for peptide synthesis and amino acid derivatives
Reliable quality: ≥98% purity, full COA, HPLC, and NMR verification
Scalable production with competitive lead times
Technical documentation and regulatory support for IND/NDA projects
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH is more than a protected peptide building block—it is a cornerstone intermediate for next-generation peptide drugs such as Semaglutide. With our CDMO capabilities, we deliver high-quality solutions tailored to pharmaceutical innovation.
